For FSLogix Profile Container to work properly, configure your antivirus to exclude the following objects, as per Microsoft’s recommendations:
Files:
%TEMP%\*\*.VHD
%TEMP%\*\*.VHDX
%Windir%\TEMP\*\*.VHD
%Windir%\TEMP\*\*.VHDX
\\server-name\share-name\*\*.VHD
\\server-name\share-name\*\*.VHD.lock
\\server-name\share-name\*\*.VHD.meta
\\server-name\share-name\*\*.VHD.metadata
\\server-name\share-name\*\*.VHDX
\\server-name\share-name\*\*.VHDX.lock
\\server-name\share-name\*\*.VHDX.meta
\\server-name\share-name\*\*.VHDX.metadata
Note: Antivirus exclusions for Microsoft Defender for Endpoint (previously Microsoft Defender Advanced Threat Protection) can be set via Parallels RAS optimizations (Windows Defender ATP category). See this KB for more info: https://kb.parallels.com/en/125071.