Best practices
The following are general best practices for using FSLogix profile containers.
For optimal performance, the storage solution and the FSLogix profile containers should exist in the same data -center location.
Exclude the VHD(X) files for profile containers from antivirus scanning to avoid performance bottlenecks.
In the case of AVD, Microsoft recommends using a separate profile container per host pool while having two active sessions.
For more information, see https://docs.microsoft.com/en-us/azure/architecture/example-scenario/wvd/windows-virtual-desktop-fslogix.
In addition to SMB locations, FSLogix introduced the Cloud Cache technology (https://docs.microsoft.com/en-us/fslogix/cloud-cache-resiliency-availability-cncpt. Please review the list of advantages and disadvantages of each approach before d)eciding on which type of locations to use.